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Joint Nutrition

CARTONICA

£29.95£59.85

The practitioner’s choice of liquid joint supplement.

Cartonica 6K takes the guess work out of choosing a joint supplement.  With 6,000mg of nutrients (6K) dissolved in an easy to take liquid, no tablet supplement comes anywhere close.

Even tablets requiring you to take two three or even more pills rarely reach more than 1,500mg.

From just £19.95 for a months supply, Cartonica is fast overtaking leading supplement brands: more nutrients, delicious to take and better price creates a winning formula.

PACKED WITH COLLAGEN II – Of the 6,000mg, 5,000mg of the blend is Type II collagen which accounts for 60% of the dry weight of cartilage found in joints.  Combined with other nutrients to support joint health, Cartonica leaves other supplements in the shade.

Start enjoying the benefits of Cartonica 6K, try it for yourself and let your joints decide.

Discover and enjoy Cartonica 6K.

  • Awesome 6,000mg of nutrients per serving
  • Dissolved nutrients more easily absorbed
  • No more gagging on tablets
  • Delicious taste and natural berry flavour

Try one bottle or take advantage of our most popular three month supply bundle for best results.

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Cartonica is the advanced liquid joint supplement which leads health conscious consumers away from tablets.

The reason is simple.  Tablet supplements can only contain a limited quantity of nutrients, typically a maximum of 1,000mg per tablet.  Some tablets, which usually sell on price, require consumers to take two or even three tablets per day and even then the nutritional content of those tablets falls well short of what is contained in Cartonica.

Cartonica was researched for supply in clinics.  It has a huge 6,000mg joint formula per serving including more type II collagen than the leading UK tablet joint supplement.  

No tablet supplement comes close to Cartonica and that is before you consider the absorption benefits of having nutrients dissolved in a liquid.

You can see the bottle label for a list of ingredients in Cartonica or click the ingredients tab.  Working with clinics, at Clinic Nutrition we also show the published evidence relating to each ingredient in Cartonica.

Some Cartonica highlights:

  • Collagen Type II is a protein made from amino acids. It accounts for 60% of the dry weight of joint cartilage. Type II collagen represents 90-95% of the total collagen in joints. The body uses amino acids and nutrients to make collagen and cartilage in joints.
  • Glucosamine Sulphate is present in the fluid which provides lubrication around joints and is a building block of cartilage.
  • Chondroitin Sulphate is a component of cartilage which retains water and is intended to enhance shock-absorbing properties.
  • MSM (Methylsulfonylmethane) contains sulphur, a building block for complex proteins called glycosaminoglycans which are in the structure of cartilage.
  • L-Carnitine is converted in the body to acetyl-L-carnitine (ALC). ALC helps maintain cell energy and protects against oxidative damage.

Cartonica also contains Vitamin C which helps the body form and repair cartilage, Vitamin D which allows the body to absorb calcium from our blood stream to make bone and Turmeric which is regarded as a natural anti-inflammatory.

Cartonica is a food supplement.  It is available in clinics primarily because it takes away the confusion for patients of trying to choose between so many different joint supplements.

Cartonica is a single product with not only more nutrients and bioavailability than tablets but it is also pleasurable and easy to consume.

Most people drink Cartonica at or before breakfast.  It comes with a handy measuring cap and you can drink Cartonica neat or diluted with water.  Whatever suits you best.

Each bottle is 500ml which represents a 33 day supply.  Once opened, just keep it in the fridge.

Upgrade your joint nutrition and start enjoying the benefits of Cartonica for yourself.

Important Allergen Advice: Contains extracts from shellfish. See label image for full list of ingredients.
Not suitable for vegetarians: Type II collagen which is a major component of articular cartilage in joints is a bovine extract.

Cartonica nutrients supporting joint health

Below is a description of each ingredient in the Cartonica blend, their purpose in joint health along with references to published studies.

  • Vitamin B12

Vitamin B12 or cobalamin is a water-soluble vitamin that plays a key role in various physiological functions. For example, healthy production of red blood cells, maintenance of nerve function and proper regulation of mood.

In addition, it also supports joint health in two ways; first, lowers the risk of bone fracture,  second, it helps normalise homocysteine levels, which may be increased in patients with joint disease. (1,2)

  • Vitamin C

Vitamin C or ascorbic acid is a water-soluble vitamin with powerful antioxidant properties. It binds to the harmful chemical species called free radicals and counteracts their negative effects.

Human studies have shown that vitamin C helps prevent cartilage loss and slows down the progression of joint diseases. (3,4)

  • Vitamin D3

Vitamin D3 or cholecalciferol is a fat-soluble vitamin. It is key to maintaining optimal bone health as it helps your body absorb calcium and phosphorus from your diet.

It helps prevent bone loss by preventing the breakdown of bone tissues and subsequent release of calcium into the bloodstream. In addition, vitamin D supplementation (either oral or using an injection) increases bone mass and reduces the risk of falls. (5,6)

  • Turmeric

Turmeric is a spice of the ginger family. It contains a powerful anti-inflammatory and antioxidant known as curcumin.

Turmeric is a safe and highly effective natural treatment for several joint diseases. Curcumin improves joint tenderness and swelling. It reduces inflammation by blocking the activity of pro-inflammatory substances, prevents cartilage degradation, and counteracts cellular damages. (7,8)

  • Green Tea Extract

Green tea extract is a rich source of potent antioxidants, polyphenols. While green tea extract is sometimes used in weight loss programmes, one of the polyphenols, epigallocatechin-3 gallate (EGCG), has been shown to ve beneficial for joint health.

EGCG helps prevent and alleviate the symptoms of joint disease through its anti-inflammatory activity. It works by blocking the activity of inflammatory substances in the cells of cartilage. (9)

  • Hydrolysed Collagen Type II

Hydrolysed collagen type II has been widely studied as a potential treatment for various joint health conditions.

Naturally-occurring type II collagen is a major component of joint cartilage. Joint diseases such as autoimmune arthritis cause a gradual loss of collagen type II and proteoglycans. This results in pain, tenderness, stiffness, and limited mobility. (10)

Laboratory study shows that administration of hydrolysed collagen type II to the culture medium stimulates the production as well as secretion of type II collagen in cartilage tissues. Moreover, ingested hydrolysed collagen type II accumulates in cartilage where it stimulates the synthesis of macromolecules that are necessary for maintaining proper functioning of the joints. (11,12)

  • Glucosamine Sulphate

Glucosamine is a naturally-occurring amino acid that plays a key role in the growth and repair of joint cartilage.

Oral glucosamine sulphate once daily for three years is found to be effective in improving the symptoms of osteoarthritis (OA). (13)

While the exact mechanism behind the benefits of glucosamine is yet to be discovered, scientists believe that it might help maintain joint health by stimulating the production of macromolecules in cartilage and blocking the effects of inflammatory substances. (14)

  • Chondroitin Sulphate

Chondroitin sulphate or Chondroitin Polysulphate is a naturally-occurring substance in joint cartilage. It is necessary for maintaining the resistance and elasticity of cartilage.  It is usually given in combination with glucosamine sulphate.

Chondroitin supplementation has been studied and is believed to help joints by one or more of the (15,16,17,18)

  • L-Carnitine

L-carnitine is an amino acid that is naturally found in the body. The body converts ingested L-carnitine into acetyl-L-carnitine, which prevents cartilage degradation and helps reduce pain associated with degenerative joint diseases such as osteoarthritis. (19)

It appears to work primarily by reducing the serum levels of pro-inflammatory substances. (20)

  • Methylsulfonylmethane (MSM)

Methylsulfonylmethane or dimethyl sulfone is an organosulphur compound naturally found in the body. It has antioxidant and anti-inflammatory properties.

As a supplement MSM has been shown to be effective in relieving joint pain and improving the functions of the joints. Interestingly, it is thought that the benefits are increased if using MSM with collagen type II. (21,22)

The beneficial effects of MSM on joint health are believed to be due to its powerful anti-inflammatory property. In addition, it might also decrease cartilage degeneration in the joints. (23,24)

References

  1. Dhonukshe-rutten RA, Pluijm SM, De groot LC, Lips P, Smit JH, Van staveren WA. Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. J Bone Miner Res. 2005;20(6):921-9.
  2. Kuzminski AM, Del giacco EJ, Allen RH, Stabler SP, Lindenbaum J. Effective treatment of cobalamin deficiency with oral cobalamin. Blood. 1998;92(4):1191-8.
  3. Chang Z, Huo L, Li P, Wu Y, Zhang P. Ascorbic acid provides protection for human chondrocytes against oxidative stress. Mol Med Rep. 2015;12(5):7086-92.
  4. Mcalindon TE, Jacques P, Zhang Y, et al. Do antioxidant micronutrients protect against the development and progression of knee osteoarthritis?. Arthritis Rheum. 1996;39(4):648-56.
  5. Sunyecz JA. The use of calcium and vitamin D in the management of osteoporosis. Ther Clin Risk Manag. 2008 Aug; 4(4): 827–836.
  6. Harwood RH, Sahota O, Gaynor K, Masud T, Hosking DJ. A randomised, controlled comparison of different calcium and vitamin D supplementation regimens in elderly women after hip fracture: The Nottingham Neck of Femur (NONOF) Study. Age Ageing. 2004;33(1):45-51.
  7. Chandran B, Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res. 2012;26(11):1719-25.
  8. Henrotin Y, Priem F, Mobasheri A. Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management. Springerplus. 2013; 2: 56.
  9. Singh R, Ahmed S, Islam N, Goldberg VM, Haqqi TM. Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB. Arthritis Rheum. 2002;46(8):2079-86.
  10. Eyre D. Collagen of articular cartilage. Arthritis Res. 2002;4(1):30-5.
  11. Oesser S, Seifert J. Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen. Cell Tissue Res. 2003;311(3):393-9.
  12. Bello AE, Oesser S. Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Curr Med Res Opin. 2006;22(11):2221-32.
  13. Reginster JY, Deroisy R, Rovati LC, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet. 2001;357(9252):251-6.
  14. Henrotin Y, et al. Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities. BMC Res Notes. 2013; 6: 115.
  15. Uebelhart D, Thonar EJ, Delmas PD, Chantraine A, Vignon E. Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study. Osteoarthr Cartil. 1998;6 Suppl A:39-46.
  16. Jomphe C, Gabriac M, Hale TM, et al. Chondroitin sulfate inhibits the nuclear translocation of nuclear factor-kappaB in interleukin-1beta-stimulated chondrocytes. Basic Clin Pharmacol Toxicol. 2008;102(1):59-65.
  17. David-raoudi M, Deschrevel B, Leclercq S, Galéra P, Boumediene K, Pujol JP. Chondroitin sulfate increases hyaluronan production by human synoviocytes through differential regulation of hyaluronan synthases: Role of p38 and Akt. Arthritis Rheum. 2009;60(3):760-70.
  18. Chou MM, Vergnolle N, Mcdougall JJ, et al. Effects of chondroitin and glucosamine sulfate in a dietary bar formulation on inflammation, interleukin-1beta, matrix metalloprotease-9, and cartilage damage in arthritis. Exp Biol Med (Maywood). 2005;230(4):255-62.
  19. Bianchi E, Di cesare mannelli L, Menicacci C, Lorenzoni P, Aglianò M, Ghelardini C. Prophylactic role of acetyl-l-carnitine on knee lesions and associated pain in a rat model of osteoarthritis. Life Sci. 2014;106(1-2):32-9.
  20. Malek mahdavi A, Mahdavi R, Kolahi S. Effects of l-Carnitine Supplementation on Serum Inflammatory Factors and Matrix Metalloproteinase Enzymes in Females with Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. J Am Coll Nutr. 2016;35(7):597-603.
  21. Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthr Cartil. 2006;14(3):286-94
  22. Xie Q, Shi R, Xu G, Cheng L, Shao L, Rao J. Effects of AR7 Joint Complex on arthralgia for patients with osteoarthritis: results of a three-month study in Shanghai, China. Nutr J. 2008;7:31.
  23. Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017 Mar; 9(3): 290.
  24. Ezaki J, Hashimoto M, Hosokawa Y, Ishimi Y. Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model. J Bone Miner Metab. 2013;31(1):16-25.
Write a review

Thank you. Please note that we reserve the right to review and remove comments as we may not make medical claims. Thank you for your comments.

Richard W.

Taunton, UK

Works for me

Cartonica has made a big difference for me. My wife takes it and we've even started taking Vitaliti as well. Excellent products and happy to recommend.

Lesley P

St Helier, Jersey

Switched from tablets

I was looking for a liquid joint product because I just can't swallow tablets. I liked the look of Cartonica and realised that it had a lot more nutrients than what I had been taking. My knees feel a lot better, so many thanks!

Karen P.

Wakefield, UK

Love Cartonica

Cartonica has really helped me. Nice to have a product which gives a lot of nutrients. Before I would buy anything, but now I feel the difference. Thank you.

Joshua L.

London, UK

The taste is ok for me and I like the fact that I am getting more nutrients. Definitely feeling more supple in my hands.

Clair D.

Staines, UK

Thank you guys. Cartonica is different from the tablets. Now I know how to read a label, I can see why Cartonica is so good!

Simon A.

Bournemouth, UK

Five Star 6K

Really like Cartonica. I bought it to help with walking and am still taking it six months later. Helps me, thank you.

Richard H.

Manchester, UK

Great product

I saw an ad and decided to try it. It is helping my joints more than what I was taking before. Happy to recommend. Thanks

Harriet B.

Watford, UK

Very good taste and a pleasure to take.

I don’t like taking supplements. I decided to try Cartonica because of the taste and because it offers more ingredients than what I usually have. I find the taste really enjoyable and it is good to know that I am getting more nutrients.

Ravi S.

Sheffield, UK

Five star Cartonica. I stopped taking supplements because I thought they were a waste of money. But I needed to try something and I find it has been helping. Thank you.

Pavel W.

London, UK

For my knees! I think I played too much football when I was younger. I take a lot of supplements but mainly I take ibuprofen :-( I wanted to try something different so I stopped other supplements and just take Cartonica. I still take ibuprofen but I am taking less. I will recommend it!

Sarah D.

Sunderland, UK

Help for a pianist

I play the piano and my fingers are starting to ache. I bought Cartonica to help my hands so I can keep playing. Cartonica gives me a feeling like someone has given my hands a warm up. I will keep taking it. Many thanks.

Giles T.

Exeter, UK

Good product

Cartonica is really good. The cold weather affects my joints and I find that Cartonica is helping my knees.

Gemma N.

Crawley, UK

No more seagull impressions :-)

I get quite a lot of products appear in my facebook. If I had a pound for every one I would be a millionaire! I saw Cartonica and it seemed a bit different. I liked the look of it and did some research. I decided to try it. First thing to say is I REALLY liked the taste! I struggle to swallow tablets, my husband says I look like a seagull choking! This is definitely a supplement I enjoy taking and I recommend it. Thank you!

Caroline G.

Hove, UK

Thank you. I am very happy with Cartonica. My husband takes it and we are on to our second bottle. We both look forward to our morning toast with Cartonica and hope it helps us stay mobile.

Nigel D

Bath, UK

Great taste, very happy with the product. Thanks.

Sandra K.

Solihull, UK

Recommendation for Cartonica

Cartonica is making a real difference. I drink it every morning. I have compared the ingredients with the tablets I was taking, there is so much more in Cartonica compared to what I was taking. Thank you.

Rohit P.

London, UK

Great product

Happy to give a review. Cartonica is definitely different to most supplements. I like the fact that it has a lot of nutrients and I can take it easily in the morning. I feel good and happy with my purchase.

Laurence H.

Birmingham, UK

Feeling positive effects

I don’t know if its psychological but I seem to be moving better. I bought it (Cartonica) for my knees and I’m feeling less stiff. Have recommended it to a few people. Thanks.

Sarah D.

York, UK

I take quite a few tablets in the morning so I bought Cartonica to try to cut down on them. I can see that it has a lot more ingredients than the supplements that I was taking so I am looking forward to seeing how it goes.

Mariam S.

Bicester, UK

Cartonica – happy with my purchase

Thank you for my recent order. I really like the taste and am happy to switch from the tablets I was taking.